Dr. Alam's research interests are centered on the study of signaling transduction pathways in various animal models of neurodegenerative diseases, including ischemic stroke and vascular dementia. His research focuses on the role of choroid plexus (ChP), the mechanism by which the choroid plexus regulates brain homeostasis by secreting cerebrospinal fluid (CSF), and the maintenance of the blood-CSF barrier by the formation of tight and adherent junctions in the choroid plexus epithelial cells. He has also been studying the role of choroid plexus in the development of Alzheimer's disease and vascular cognitive impairment and dementia, especially with respect to the breakdown of the blood-CSF barrier, the role of neuroinflammation, and leukocyte infiltration in the brain. His research has the potential to elucidate the various cellular and molecular mechanisms by which the blood-CSF barrier is impaired, with a particular focus on the choroid plexus SPAK signaling pathway as a potential therapeutic target.

Dr. Alam has extensive research experience in developing animal models of various neurodegenerative and cerebrovascular diseases, including the use of advanced surgical techniques, behavioral studies, and various histological and biochemical techniques. He has developed substantial expertise in the use of transgenic animal models, Extracellular Vesicles (EV) communication research, state-of-the-art multi-omics approaches, microscopy, molecular genetics, and cellular and molecular biology techniques. The long-term research interest of Dr. Alam is to apply the findings from his research to the development of precision medicine, thus allowing the development of novel biomarkers and therapies for the treatment of various neurodegenerative diseases.

Outside the lab, Dr. Alam actively attends scientific conferences to stay current with advancements in neuroscience. Besides, he likes to spend quality time with his family, and for this, he likes to go on outings and join gatherings with his family and friends. He believes this gives him an opportunity to relax and maintain a healthy work-life balance.

Education & Training

· Postdoctoral Associate (Neuroscience), Department of Environmental & Occupational Health, University of Pittsburgh, USA.

· PhD (Neuroscience), Doshisha University, Kyoto, Japan.

· M.Sc & B.Sc (Biochemistry & Molecular Biology), Rajshahi University, Rajshahi, Bangladesh.